Pain is an unpleasant sensation and demands instant relief. Aceclofenac is one of the selective drug having low solubility in water. The present research work was done to increase the water solubility of Aceclofenac by using Polyethylene Glycol 6000 and Croscarmellose. The solid dispersion was prepared by using three different methods like physical mixture, kneading method and solvent evaporation technique in 1:1 and 1:2 ratio. All the batches were evaluated for angle of repose, bulk density, compresiblity, Moisture uptake, solubility and drug content. The final batch was evaluated by Differencial Scanning Colorimetry (DSC).
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